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Showing posts with label Idera. Show all posts
Showing posts with label Idera. Show all posts

Sep 3, 2008

Idera Pharmaceuticals : Milestone Payment Under Asthma and Allergy Collaboration

Sept. 2, 2008 - Idera Pharmaceuticals, Inc. (Nasdaq: IDRA), announced that it will receive a milestone payment from Novartis under the two companies' research collaboration and license agreements. Under the terms of the agreement, the payment was triggered by the initiation of a Phase 1 clinical study by Novartis of QAX935. QAX935 is a novel agonist of Toll-Like Receptor 9 (TLR9) exclusively licensed by Idera to Novartis...



...About the Collaboration

In June 2005, the Company and Novartis announced they had entered into research collaboration and license agreements for the discovery, optimization, development, and commercialization of TLR9 drug candidates targeting asthma and allergy based on Idera's proprietary Immune Modulatory Oligonucleotide (IMO(TM)) technology platform. The agreements are structured in two phases. During the research collaboration phase, the Company and Novartis have been working together to evaluate novel IMOs from which Novartis may select IMO candidates for further development through human clinical "proof of concept" trials. Based on the results, Novartis may then elect to implement the commercialization agreement, complete the development and commercialize one or more of the IMO candidates... Idera Pharmaceuticals' Press Release -

Apr 16, 2008

Idera Pharmaceuticals : Preclinical Data of its Toll-Like Receptor - Targeted Compounds at AACR Meeting

Apr 09, 2008 - Idera Pharmaceuticals, Inc. (Nasdaq: IDRA) announced that preclinical data from its Toll-Like Receptor (TLR) programs will be presented at the 2008 Annual Meeting of the American Association for Cancer Research (AACR) being held in San Diego, CA, April 12-16, 2008...
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Abstract 2078 entitled "Antitumor activity of IMO-2055, an agonist of TLR9, in combination with erlotinib and bevacizumab in non-small cell lung cancer xenografts in mice" will be presented by Idera. In the study, IMO-2055, a TLR9 agonist, was evaluated in combination with erlotinib and bevacizumab in preclinical mice models... Idera Pharmaceuticals' Press Release -

Sep 9, 2007

Idera Pharmaceuticals, Phase 1 Study Evaluating

September 6, 2007 – Idera Pharmaceuticals, Inc. (AMEX: IDP), today announced interim results from a Phase 1 clinical trial being conducted by the Company evaluating IMO-2055, the Company’s lead Toll-Like Receptor (TLR) 9 agonist, in combination with gemcitabine and carboplatin in patients with advanced solid tumors......The data presented in the poster concern 19 patients evaluated for safety and also for efficacy prior to June 2007, including eight patients with non-small cell lung cancer (NSCLC)...
[PDF] Idera Pharmaceuticals' Press Release -