Blog Archive
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2008
(297)
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April
(50)
- NuRx Pharmaceuticals : Phase I Clinical Trial of F...
- Replidyne Discontinues Phase III Trial
- InterMune : Progress on Pirfenidone in Idiopathic ...
- MedImmune and Infinity : Preclinical Data Highlig...
- Diffusion Pharmaceuticals : patent no. 7,351,844 e...
- Micromet : Phase 1 Clinical Trial with MT110, the ...
- Sorin : approval to market heart-lung machine in J...
- Gene Express : licensing agreement with University...
- Genentech : "AVAiL" Phase III Study of Avastin Plu...
- Spectrum Pharmaceuticals : Preclinical Data Demons...
- Kosan : Phase 2 Trial of Epothilone KOS-1584 in No...
- Infinity Pharmaceuticals' Hedgehog Antagonist Dela...
- Oncolytics Biotech : Dose Escalation in Combinatio...
- Alfacell's ONCONASE : Potential as Radiation Sensi...
- Lilly's ALIMTA : European Approval for Histologica...
- Rosetta Genomics : Agreement With West Coast CLIA ...
- Pharmaxis : CF Trial in Children Returns Positive ...
- MedImmune : Asthma Program with Start of a Phase 2...
- Transave : Study Confirms Anti-Infective ARIKACE E...
- Antisoma and Novartis : phase III lung cancer tria...
- UCB : Phase II results for CDP791 in non-small cel...
- Dinamika : A New Asthma Treatment Introduced by Ru...
- SkyePharma : exclusive License Agreement with Kyor...
- eResearchTechnology, Inc. and nSpire Health, Inc. ...
- Alnylam : ALN-RSV01 in Adult Lung Transplant Pati...
- Critical Therapeutics : Phase I Clinical Trial of ...
- bioMerieux & University of Sunderland : Collaborat...
- TaiGen : Positive Data From the Phase II Study of ...
- Aeolus Pharmaceuticals : AEOL 10150 Protects Lungs...
- AVEO’s Novel Triple VEGF Receptor Inhibitor... Cli...
- Idera Pharmaceuticals : Preclinical Data of its To...
- Kamada : New Orphan Drug Designation by the FDA, f...
- Yale and Asuragen : a microRNA Can Reduce Lung Can...
- Aradigm : Trial of Lung Rx's Inhaled Treprostinil
- KaloBios : Phase 1/2 Trial of Humaneered Monoclona...
- Kamada : Phase III Clinical Trial with Intravenous...
- Cortex : Enrollment in Opiate Induced Respiratory ...
- Actelion and Nippon Shinyaku : pulmonary arterial ...
- Angeion : Medical Graphics Platinum Elite Series P...
- Ceragenix Pharmaceuticals : CeraShield(TM) Coated ...
- NIR Diagnostics : agreement with a European medic...
- Third Wave’s InPlex CF Molecular Test : FDA Clearance
- Celgene : Amrubicin Receives FDA Orphan Drug Desig...
- Lorus : initiation of IND-enabling toxicology stud...
- Poniard Pharmaceuticals : Commercial Manufacturing...
- OXiGENE : Phase II NSCLC Trial of ZYBRESTAT(TM) in...
- Discovery Labs and Chrysalis Technologies : about ...
- MediciNova : Phase II Clinical Trial of MN-221 in ...
- Vertex : Positive Results for VX-770, an Oral Inve...
- Philips : completion of Respironics acquisition
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April
(50)
Apr 25, 2008
Infinity Pharmaceuticals' Hedgehog Antagonist Delays Tumor Growth Following Chemotherapy in Preclinical Model of Small Cell Lung Cancer
Apr 15, 2008, 2008 - Infinity Pharmaceuticals, Inc. (Nasdaq:INFI) announced that preclinical data from a model of small cell lung cancer (SCLC) show that following treatment with chemotherapy, once-daily oral administration of IPI-926 leads to a statistically significant delay in tumor re-growth, compared to vehicle control (p=0.01). These results suggest that inhibiting the Hedgehog pathway with IPI-926, Infinity's novel, potent Hedgehog pathway antagonist following chemotherapy delays tumor recurrence in SCLC. These data were presented today during the Annual Meeting of the American Association of Cancer Research (AACR) in San Diego, California... Infinity Pharmaceuticals' Press Release -