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Jul 25, 2008

Resolvyx Pharmaceuticals : First In-Vivo Data Showing Resolvins Suppress IL-23 and IL-17, Key Mediators of Inflammatory Disease

July 3, 2008 -- Resolvyx Pharmaceuticals, Inc., the leading resolvin therapeutics company, announced that a research team led by a Resolvyx scientific advisor and a company co-founder has demonstrated that the resolvin E1 (RvE1) effectively suppresses IL-23 and IL-17, two key inflammatory mediators of chronic inflammatory disease, in a preclinical model of asthma. RvE1 is the active ingredient in RX-10001, one of Resolvyx’s leading clinical candidates. The paper, titled "Resolvin E1 regulates interleukin 23, interferon-δ and lipoxin A4 to promote the resolution of allergic airway inflammation," published in the journal Nature Immunology... Resolvyx Pharmaceuticals' Press Release -