Following an antibiotic washout period, 36 patients will be enrolled to receive daily inhaled liposomal ciprofloxacin for a period of 28 consecutive days. The primary efficacy endpoint will be treatment of respiratory infection measured as the change in the density of Pseudomonas Aeruginosa bacterial colony forming units (CFU) in the sputum over the treatment period. Secondary endpoints will include pulmonary function measurements and respiratory symptoms. The study is being conducted in leading bronchiectasis centers in the United Kingdom... Aradigm's Press Release -
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Jun 23, 2008
Aradigm : Phase 2 Study of Inhaled Liposomal Ciprofloxacin in Bronchiectasis
June 19, 2008- Study Will Explore New Treatment of a Severe Respiratory Disease Condition with Unmet Medical Need -Aradigm Corporation (OTCBB: ARDM) (the "Company") announced it has initiated a multicenter Phase 2 clinical trial of its inhaled liposomal ciprofloxacin in adult patients with non-cystic fibrosis bronchiectasis.