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Jun 10, 2008

GlaxoSmithKline : New data on MAGE-A3 cancer immuno therapy support novel options of treating non-small cell lung cancer and melanoma

30 May 2008 - New data presented by GlaxoSmithKline (GSK) highlighted the potential of its investigational MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (ASCI) through results of three studies evaluating highly targeted immunotherapy as a treatment for metastatic melanoma and non-small cell lung cancer (NSCLC). These data were presented at the 2008 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago[Abstract Nos: 9065[i], 9045[ii] and 7501[iii].

A randomised, open label Phase II study designed to evaluate two different formulations of the MAGE-A3 ASCI in patients with metastatic melanoma has been conducted. In this study, the ASCI, which is a combination of MAGE-A3 recombinant protein and a GSK proprietary Adjuvant System, was evaluated and resultant data suggest a positive trend for clinical response... GlaxoSmithKline's Press Release -